重组人 OSM 蛋白(His标记)
货号：106469 编号：XFBM494
CAS号： 规格：Oncostatin M,oncostatin-M,OSM
包装：10 μg 保质期：365天
保存条件：-20℃保存
DESCRIPTION | ||
Gene Name Synonym | Oncostatin M,oncostatin-M,OSM | |
Species | Human | |
Accession | P13725 | |
Source | E.coli | |
SPECIFICATIONS | ||
Amino acid sequence: | A DNA sequence encoding the Human OSM protein(Ala 26-Arg 221) was expressed with a 6×His tag at the N terminus. | |
Molecular Weight: | Approximately 23.1 kDa. | |
Purity: | >95.0% as determined by SDS-PAGE | |
Endotoxin: | <1.0 EU/μg of the protein by the LAL method. | |
Formulation: | Lyophilized from sterile PBS, pH 7.4. Normally 5%-8% trehalose and mannitol are added as protectants before lyophilization. | |
Reconstitution: | Dissolved in sterile water, it is recommended to add 0.1% HSA or BSA for long-term preservation. | |
STORAGE | ||
Stability and Storage | 12 months from date of receipt at -20°C to -70°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for almost 6 months (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage. | |
BACKGROUND | ||
Oncostatin M (OSM) is a multifunctional growth regulator belonging to the interleukin-6 subfamily of cytokines that has dual functions of inhibiting tumor cell lines and stimulating the proliferation of AIDS-KS cells. OSM is considered as a pleiotropic cytokine that signals through cell surface receptors typeⅠand typeⅡ both of which share the similarity of containing protein gp130 and takes part in many bio metabolism processes including liver development, hematopoiesis, inflammation, bone formation, and destruction and possibly CNS development. OSM was previously identified by its ability to inhibit the growth of cells from melanoma and other solid tumors. It also has been reported that OSM, like LIF, IL-6, and G-CSF, can inhibit the proliferation of murine M1 myeloid leukemic cells and can induce their differentiation into macrophage-like cells. OSM is synthesized by stimulated T-cells and monocytes. Furthermore, the effects of OSM on endothelial cells suggest a pro-inflammatory role for OSM and endothelial cells possess a large number of OSM receptors. | ||
Data | ||
SDS-PAGE | Bioactivity | |
| ||
Recombinant Human OSM Protein was determined by SDS-PAGE with Coomassie Blue. | ||
快递服务
江浙沪皖用户邮费为10元，其他地区用户邮费为20， 国际运费请咨询sales@xfnano.com。购买满 500.0 元免运费。如果库存显示为0， 请电话或邮件和销售确认，免费热线电话：400 025 3200邮件：sale@xfnano.com 感谢您的支持！
推荐商品
